Laufende Forschung
Gemeinsame experimentelle Forschungsprojekte
- Extracorporeal xenoperfusion of porcine extremities to assess the effect of transgenic modification of donor pigs R. Rieben, E. Vögelin, M. Constantinescu, R. Sfriso, A. Bongoni (Melbourne), N. Klymiuk (München), E. Wolf (München), J. Seebach (Genf), H. Niemann (Hannover)
- Characterization of the immune mechanisms of allograft rejection and acceptance in hind-limb transplanted rats R. Olariu, F. M. Leclère, E.Vögelin, A. Taddeo, J. Leckenby, D. Dzhonova, R. Rieben
- Extracorporal limb perfusion for delayed macroreplantation using cytoprotective agents R. Rieben, E. Vögelin, M. Constantinescu, M. Abdelhafez, D. Sutter, J. Schnider, A.Taddeo, R. Sfriso, P. Garimella
- The role of locally used tacrolimus (FK 506) in nerve regeneration R.Olariu, J. Leckenby, R. Rieben, A.Taddeo, E. Hever, M. Constantinescu, E. Vögelin
- Targeting the lymphatic system for modulating immune rejection and promoting tolerance in vascularized composite allotransplantation R. Olariu, A. Taddeo, J. Leckenby, E. Vögelin, R Rieben
- Effect of lymphatic tissue transfer on vascularized composite allografts A Taddeo, R. Olariu, E. Vögelin, R Rieben
- Localized immunosuppression with TGMS-TAC for loing-term survival of VCA in a rat model D. Djonova, A. Taddeo, R.Olariu, J. Leckenby, R. Rieben, M. Constantinescu, E. Vögelin
- Tissue engeneering of vascularized nerve A. Taddeo, Jerome Duisit, I. Lese, R. Olariu, Tsering Wüthrich, Lengelè
- Site specific immunosuppression for long-term maintenance of vascularized composite allotransplantation: validation of efficay large animal model R. Olariu, A. Taddeo, R. Rieben, E. Vögelin, M. Constantinescu
- Development of vascularized nerve scaffold using perfusion-decellularization and recellularization Tsering Wüthrich, Ioana Lese, David Haberthür, Cédric Zubler, Ruslan Hlushchuk, Ekkehard Hewer, Louis Maistriaux, Pierre Gianello, Benoît Lengelé, Robert Rieben, Esther Vögelin, Radu Olariu, Jérôme Duisit, Adriano Taddeo
Plastische Chirurgie Experimentelle Forschungsprojekte
- Lymph node including hindlimb transplantation in rats – A feasibility study R. Olariu, J. Leckenby, I. Lese, D. Graf
- Increasing Perforator Flap Survival by Augmenting Arterial Inflow and/or Decreasing Venous Tone: Experimental Study R. Olariu, H. Moser, I. Lese, M. Constantinescu
- Modification of the VRAM flap to allow univariate arterial anastomosis analysis C. Fischlin, J. Leckenby
- The role of Endothelial Progenitor Cells in vascularized composite allotransplantation J. Leckenby, R. Olariu, O. Bleiziffer
- Increasing perforator flap survivial by laser delay: A study of an alternative method to surgical delay in a rat model R. Olariu, A. Taddeo
- The role of nanoparticles in preventing seroma formation on a rat model R. Olariu, I. Lese, A. taddeo, M. Constantinescu
- In-vivo proof of Laser-assited vascular anastomosis (LAVA) in pigs: An alternative to suturing J. Leckenby, M. Constantinescu
- Use of nanoparticles to increase perforator flap Survival R. Olariu, I. Lese, A. Taddeo, M. Constantinescu
- Tissue engeneering of vascularized nerve A. Taddeo, Jerome Duisit, I. Lese, R. Olariu, Tsering Wüthrich, Lengelè
- CoVasc: Unravelling consequences of SARS CoV-2 mediated inflammatory immune responses in heart and vasculature M. Holwerda, N. Sorvillo, R. Olariu, M. Constantinescu
- Mixed Metal Oxide Nanoparticle Formulations for the Treatment of Seroma I. Lese, H. Sophie Scheer, A. Taddeo, M. A. Constantinescu, Radu Olariu
- Acute skin perfusion changes due to conditioning: the role of ischemic conditioning, remote ischemic conditioning, and pharmacologic conditioning in healthy volunteers Jens Rothenberger, M. Constantinescu
- Decellularized vascularized rabbit nerve grafts D. Sutter, G. Robinson, E. Vögelin
- Quantitative impact analysis of remote ischemic conditioning and capsaicin application on human skin microcirculation Rothenberger, Jens; Wittwer, Matthias; Tschumi, Christian; Constantinescu, Mihai Adrian; Daigeler, Adrien; Olariu, Radu
- The anatomical reliability of the superficial circumflex iliac artery perforator (SCIP) flap Cédric Zubler, David Haberthür, Ruslan Hlushchuk, Valentin Djonov, Mihai A Constantinescu, Radu Olari
- Delivery of Rapamycin using In Situ Forming Implants Promotes Immunoregulation and Vascularized Composite Allograft Survival Damian Sutter, Dzhuliya V Dzhonova, Jean-Christophe Prost, Cedric Bovet, Yara Banz, Lisa Rahnfeld , Jean-Christophe Leroux, Robert Rieben, Esther Vögelin, Jan A Plock, Paola Luciani, Adriano Taddeo, Jonas T Schnider
Klinische Forschungsprojekte
- Soft Tissue Infections in Patients suffering from Polytoxicomania Ch. Tschumi, S. Rossi, J. Rothenberger, M. Constantinescu
- Lymph node Identification in skin Malignancy using Indocyanine green Transcutaneously (LIMIT) Study R. Olariu, J. Leckenby, I. Lese, M. Constantinescu
- Outcome of medial thigh lifts with limited skin undermining and periosteal anchoring of dermal flaps in post-bariatric patients R. Olariu, T. Hirschi, I. Lese, M. Constantinescu
- A single-unit retrospective study on free flaps: a 10-year experience I. Lese, R. Biedermann, S. Rossi, M. Constantinescu
- Comorbidities and complications: a single-center prospective study on distal lower extremity defect reconstruction with propeller flaps R. Olariu, I. Lese, M. Constantinescu
- ALT vs. Scapular Flap for Lower R. Olariu, D. Harder, R. Ipaktchi, J. Leckenby, M. Constantinescu
- Turnover Sartorius Flap - a reliable local coverage for expose inguinal vessels G. Heil, R. Olariu, M. Constantinsecu
- Remote ischemic preconditioning in reconstruction of the lower limb I. Bayard C. Tschumi M. Constantinescu
- Are the classical radiological silicone implant rupture sings still reliable? Ch.Tschumi, A. Koch, M. Constantinescu
- Skin and subcutaneous tissue samples discarded after elective reconstructive surgery of patients: Use for preparation of in vitro cell culture models of skin made up of several cell types and suitable for drug development and cosmetic safety studies - 3DSKIN R. Olariu, M. Constantinescu
- The incidence of complications and lymphedema after axillary and inguinal lymphadenectomy. An evaluation of possible risk factors V. Hürlimann, R. Olariu, M. Constantinescu
- Early and delayed flap coverage in the lower extremity - a single center review H. Scheer, R. Olariu, M. Constantinescu
- Interfascicular nerve Splitting technique in latissimus dorsi muscle Transfer for facial palsy to minimize donor site morbidity I. Lese, A. Grobbelaar
- Retrospektive Analyse freier Fibulalappen zur Qualitätssicherung im Zeitraum 2009 - 2019 J.S. Schenkel, R. Olariu, M. Constantinescu
- Pre versus subpectoral implantbased breast reconstruction after skin-sparing mastectomy or nipple-sparring mastectoma (OPBC -02/PREPEC) - A pragmatic, multicenter, randomized, superiority trial M. Constantinescu
- An unusual clinical presentation of necrotizing fasciitis A. Papanikolaou, M. Constantinescu
- Current Patterns of Care of Dermatofibrosarcoma Protuberans (DFSP) or DFSP with fibrosarcomatous transformation: A study by the TARPSWG (Study TARPSWG - 2008) R. Olariu, Jeffrey Farma
- Validation of a predictability for vascular compromise in free flap reconstruction: a observational prospective study I. Lese, M. Constantinescu
- Pleomorphic dermal Sarcoma (PDS) H. Scheer, R. Olariu
- Postoperative seroma treatment - a monocentric, retrospective observational study I. Lese, M. Constantinescu
- A single center retrospective study to evaluate the flap surgery on sarcoma patients and their complications inclusive in the setting of neoadjuvant and adjuvant radiation I. Lese, M. Constantinescu
- Novel inorganic nanohybrids for seroma management I. Lese, S. Loy (ETH), J. Goldhahn (ETH), K. Herrmann (ETH)
- Outcome assessment of patients who underwent augmentation mastopexy planned with the use of 3D computer technology A. Papanikolaou, D. Erni, M. Constantinescu
- Post bariatric contour deformity correction: An endeavor to establish objective criteria nationally J. Brühlmann, I. Lese, A. Grobbelaar, C. Fischlin, M. Constantinescu, R. Olariu
- Product Surveillance Registry Platform Base Clinical Investigation Plan I. Lese, R. Olariu
- Post Market Clinical Aggregated Data Collection Survey on Visionsense™ VS3 Iridium System for Safety and Performance Evaluation (the “Survey”) I. Lese, R. Olariu
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Review of the outcome of the treatment concept for necrotizing fasciitis in patients treated in the University Hospital Bern from 2008-2018 A. Papanikolaou, M. Constantinescu
Handchirurgie Experimentelle Forschungsprojekte
- Locally delivered Immunosuppression for vascularized composite Allotransplantation A. Taddeo, E. Vögelin
- Delivery of rapamycin using in situ forming implants induces immunoregulatory mechanisms promoting vascularized composite allograft survival D. Sutter, D. V. Dzhonova, J.-C. Prost, C. Bovet, Y. Banz, J.-C. Leroux B.Pharm, R.Rieben, E.Vögelin, J. A. Plock, P. Luciani, A. Taddeo, J. T. Schnider,
- Local Immun supression and PRORP Ischemia and reperfusion S. Hirsiger, J. Wang, I. Hoyos
Klinische Forschungsprojekte
- Kispi - Finger and handinjuries in a pediatric emergency department - a 15 month review from a Swiss tertiary hospital C. Surke, E. Vögelin
- Treatment of metacarpal fractures by means of a photodynamic polymer (Illuminoss®) C. Surke, E. Vögelin
- Are there any astronomical or seasonal risk factors for dog or cat bite injuries? R. Meier, L. Haug, P. Schmid, C. Surke, E. Vögelin
- Ultrasonographic evaluation of Peripheral nerves after traumatic injury and nerve repair (median, ulnar or radial nerves) B. Juon Personeni, E. Vögelin
- Tournequet related ischemia reperfusion injury and netosis S. Hirsiger, E. Vögelin
- Erfassung von Komplikationen nach Beugesehnenbehandlung mit CAM (Controlled Active Motion) Schema E. Oberfeld, Ch. Wirz
- Prospektive analysis of tisue toxicity of Octenisept in hand wounds S. Langen, C. Surke, E. Vögelin
- Complications after surgical decompression of peroneal nerve ganglions: A retrospective case review C. Wirtz, S. Rossi, E. Vögelin
- Is Every MRI Suspected Schwannoma a Benign Tumor? E. L. Schmid, R. Meier, E. Vögelin
- Beurteilung der funktionellen Nervenregeneration mittels Diffusions-Tensor-Bildgebung im MRI D. Merky, E. Vögelin
- Pyrocarbon Interposition Arthroplasty (Amandys) for the Wrist: Early Results of a Prospective Case Series R. Meier, C. Surke, E. Bodmer, D. Bignion; E. Vögelin
- Retrospektive Analyse nach Xiapex-Infiltration und Vergleich zur partiellen Fasziektomie (M. Dupuytren-MD) S. Kohl, E. Vögelin
- Septic Arthritis of the Small Joints and Wrist R. Meier, T. Wirth, P. Sendi, E. Vögelin
- Langzeit Follow up - Retrospektive Analyse nach Xiapex-Infiltration und Vergleich zur partiellen Fasziektomie (M. Dupuytren-MD) S. Sutter, E. Vögelin
- Radiolunotriquetral Bone-Ligament Autograft as an additional L. Haug, D. Bignion, E. Vögelin
- Analysis of animal bites concerning duration of hospitalization, overall treatment and Costs L. Haug, R. Meier, E. Vögelin
- Biomechanical analysis of carpal instability after resection of distal pole of the scaphoid, partial and total trapeziectomy L. Haug, E. Vögelin
- Dorsal bone-ligament-bone reconstruction of chronic lunotriquetral instability T. Adler, R. Meier, E. Vögelin
- Does the anatomy of the cubital tunnel give a hint of ulnar nerve instability? T. Adler, J. Henning, E. Vögelin
- Semiokklusive Folienbehandlung bei Fingerkuppenverletzungen T. Pastor, L. Haug (Betreuung Masterstudentin, ab 2017)
- Sonography-guided percutaneous A1 pulley release D. Sutter, E. Vögelin
- Ergebnisse nach Beugesehnenverletzungen der Langfinger und des Daumens in den Zonen 1- 3: eine (Schweizer) Multicenter-Studie: Erfassung von möglichen Einflussfaktoren auf das Behandlungsergebnis PD Dr. med. M. Calcagni USZ
- Diagnostic Ultrasound in Carpal Tunnel Syndrome: Outlet ratio S. Hirsiger, E. Vögelin
- Results after adhesiolysis of extensor and flexor tendons in inpatients with and without continuous plexus anesthesia L. Haug, E. Vögelin
- Retrospective Data Analysis: Ultrasound in Carpaltunnel Syndrome: Inlet and Outlet Ratio S. Hirsiger, E. Vögelin
- Treatment of fractures of the hand with a photodynamic polymer (Illuminoss® II) C. Surke, E. Vögelin
- Comparing treatment of basic phalangeal fractures with intramedullary cannulated headless compression screws versus plating K. Silins, L.Haug, E. Vögelin
- Retrospective Data Analysis: Revision Rates of Pyrocardan in CMC I Osteoarthritis S. Hirsiger, E. Vögelin
- RCPI - Capitatum Oberflächenersatz mittels RCPI® in Kombination mit Entfernung der proximalen Handwurzelreihe (PRC) bei Panarthrose im Handgelenk S. Roner, E. Vögelin
- Sensorische Wiederherstellung digitaler Nerven nach primärer Reparatur mit mikrochirurgischer epineuraler End -zu-End Neurorraphie allein oder in Kombination mit Tisseel® - RET L. Fuest, E. Vögelin
- Sonographisch durchgeführte perkutane A1-Ringbandspaltung bei Ringbandstenose - eine retrospektive Fallserie D. Sutter, E. Vögelin
- Bone and Joint infections of the hand P. Sendi, R. Meier
- Giant cell tumors of the Synovia: Prediction of recurrence rates of intra and extraarticular tumors of the extremities - a retrospective data analysis in a single center S. Hirsiger, J. Brühlmann, A. Grobbelaar, R. Olariu E. Vögelin
- Midterm clinical outcome of Salvage Gracilis flaps for defects of the hand T. Pastor, L. Haug, E. Vögelin
- Retrospektive Fall-Kontrollstudie der arthroskopisch versus offen versorgten perilunären Luxationen R. Liechti, D. Merky, E. Vögelin
- Systematisches Review zur Versorgung der perilunären Luxationen und Luxationsfrakturen R. Liechti, S. Hirsiger, E. Vögelin
- Posttraumatic Enterobacter Cloacae Monoinfections in Upper Extremity – a Case Series L. Dietrich, E. Vögelin
- Retrospektives chirurgisches Outcome und Komplikationsanalyse des eigenen Patientenkollektivs mit allodynischen und hyperalgischen Beschwerden der unteren Extremität R. Ipaktchi, E. Vögelin
- Systematische Review und Meta-Analyse Collagenase vs. Limitierte Fasziektomie bei M. Dupuytren R. Liechty, E. Vögelin
- Datenbank zur Plexus brachialis Läsion R. Ipaktchi, E. Vögelin
- Retrospektive Kohortenstudie zur Analyse von klinischen, histologischen und ökonomischen Ergebnissen der hirurgischen Therapie verglichen mit der Kollagenase-Injetktion bei Patienten mit Morbus Dupuytren R. Liechty, E. Vögelin
- Lebensqualität und Arbeitsbedingungen von Schweizer Handchirurg:innen – eine nationale Befragung T. Pastor, L. Dietrich, E. Vögelin
- Posttraumatic entrapment of the suprascapular nerve due a complex scapular fracture - a case report L. Dietrich, E. Vögelin
Handtherapie Forschungsprojekte
Handtherapie Forschungsprojekte
- Ergebnisse der Beugesehnenverletzungen der Langfinger und des Daumens in den Zonen 1-3: eine (Schweizer) multicenter Studie: Erfassung von möglichen Einflussfaktoren auf das Behandlungsergebnis B. Tobler, V. Beckmann-Vries, L. Schrepfer, E. Vögelin, A. Kämpfen, M.Calcagni
- Acceptability and safety of 3D printed wrist-based splints compared to plaster casts for the treatment of non-surgical distal radius- and scaphoid fractures: a randomized feasability study B. Tobler, F. Schuind, L. Voillat, P. Kammermann, E. Vögelin
- The systematic review of true active motion rehabilitation protocols and their replicability for patients with a flexor tendon injury in Zone I/II Tamara Hauri, Bernadette Tobler- Ammann, Esther Vögelin, Miriam Marks, Eling de Bruin, Rob de Bie
- The postoperative management of flexor tendon repairs: practice patterns around the world Tamara Hauri, Bernadette Tobler- Ammann, Esther Vögelin, Rob de Bie, Miriam Marks, Eling de Bruin
- Psychometric measurement properties of the German Version of the Michigan Hand Questionnaire in patients after flexor tendon repair Tamara Hauri, Bernadette Tobler- Ammann, Esther Vögelin, Eling de Bruin, Rob de Bie, Miriam Marks
- Early active motion in the rehabilitation of flexor tendon injuries: Short splint versus relative motion: a pilot randomized controlled pilot trial Tamara Hauri, Miriam Marks, Esther Vögelin, Eling de Bruin, Rob de Bie, Bernadette Tobler- Ammann
- The evaluation of return to work after flexor tendon injury: a mixed method study Tamara Hauri, Miriam Marks, Esther Vögelin, Eling de Bruin, Rob de Bie, Bernadette Tobler- Ammann